Our Lead Optimisation services focus on the delivery of key target compounds. Our expertise in route design and parallel synthesis of small focused library sets of typically 5 to 50 compounds ensures your leads are efficiently optimised.
Our in-house custom synthesis capability allows us to quickly and cost effectively synthesise, optimise and progress leads to the next stage of development.
Typical services include:
- Route scouting/design followed by first known synthesis
- Custom synthesis of analogues of lead and second generation compounds
- Custom synthesis of focused library sets (5-50 compounds, 5-250mg, >95% purity)
- Rapid scale-up of high priority compounds
We provide a value added Lead Optimisation service with an emphasis on compound quality, purity and pharmacological properties. We fully support our chemists enabling them to work on your programmes more effectively.
