Offering clients a huge amount of chemistry experience and technical expertise, our Lead Optimisation (Medicinal Chemistry) services focus on the delivery of key target compounds. With a very high success rate and an established track record, this really is our bread-and-butter. Our medical chemistry service expertise in route design and parallel synthesis of small focused library sets of typically 5 to 50 compounds ensures your leads are efficiently optimised.
Our in-house custom synthesis capability and state-of-the-art equipment allows us to quickly and cost effectively synthesise, optimise and progress leads to the next stage of development. We have over 25 PHD-qualified FTEs and clients have utilised our experts for a period of a few months up to over a year to support their projects.
Typical Lead Optimisation (Medicinal Chemistry) services include:
- Route scouting/design followed by first known synthesis
- Custom synthesis of analogues of lead and second generation compounds
- Custom synthesis of focused library sets (5-50 compounds, 5-250mg, >95% purity)
- Rapid scale-up of high priority compounds
We provide a value added Lead Optimisation (Medicinal Chemistry) services with an emphasis on compound quality, purity and pharmacological properties. We fully support our chemists enabling them to work on your programmes more effectively.