Our Lead Optimisation (Medicinal Chemistry) services focus on the delivery of key target compounds. Our expertise in route design and parallel synthesis of small focused library sets of typically 5 to 50 compounds ensures your leads are efficiently optimised.
Our in-house custom synthesis capability allows us to quickly and cost effectively synthesise, optimise and progress leads to the next stage of development.
Typical Lead Optimisation (Medicinal Chemistry) services include:
- Route scouting/design followed by first known synthesis
- Custom synthesis of analogues of lead and second generation compounds
- Custom synthesis of focused library sets (5-50 compounds, 5-250mg, >95% purity)
- Rapid scale-up of high priority compounds
We provide a value added Lead Optimisation (Medicinal Chemistry) service with an emphasis on compound quality, purity and pharmacological properties. We fully support our chemists enabling them to work on your programmes more effectively.
